Clinical Evidence

A Breakthrough Technology Using Nonin Medical’s Dynamic Compensation™ Algorithm for Neonatal/Pediatric Cerebral Oximetry

Jill Wroblewski, MS; Franz Ulrich, MS; Aaron Lobbestael, MS; and Matthew Prior, Ph.D; Nonin Medical, Inc., Plymouth, Minnesota


Light attenuation properties of brain tissue change with age and can impact near-infrared spectroscopy (NIRS) cerebral oximetry
systems. Use of 1) multiple sensors for different age groups, and 2) incorporation of age into the algorithm have both been used
previously in an attempt to minimize the impact of this effect. In contrast, the EQUANOX™ Advance Oximetry System with the 8004CB
sensor incorporates Nonin’s proprietary, patent-pending Dynamic Compensation™ algorithm to account for the variability in light
absorption-scattering characteristics of a child’s developing brain tissue. This methodology allows for adjustment based on each
patient’s developmental status rather than relying on an age-based or broad-group estimate.

Continue reading about the Dynamic Compensation algorithm.