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Numerous advances have sprung up in the field of resuscitation. One of the promising new tools is cerebral oximetry, or rSO2, which measures the oxygenation of the brain. Cerebral oximetry is a valuable guide for clinicians to make informed decisions about optimizing the bundle of care for patients in cardiac arrest. Join Drs. Lurie and Holley as they explore the technology that can help us “save the brain” and save lives.